Functional Annotation and Classification of Proteins of Prokaryotes

FACoP.v2: NEW version May 2023
What's New:
1) Input is a DNA file (.fna, .fasta, or .fa) and an .gff or .gff3 annotation file
2) Option to perform 'de novo' annotation using only a DNA file
3) Operon prediction is now included
4) PFAM is depreciated: for this reason we removed PFAM from the annotation pipeline
FACoP is a supporting system for FUNAGE-Pro to classify genes for Gene Set Enrichment Analysis. FACoP will annotate proteins for: GO, InterPro(IPR), KEGG-orthology KO, KEGG-pathways, Operons, eggNOG, COG, and KEYWORDS.
For large projects, a stand-alone version (Linux only) should be used; it can be downloaded here: download
If you don't get results most likely the input files are not correct
  • Check if the headers in the fasta file are identical to the first column in the GFF file
  • FACoP use locus-tags as indentifiers, check if your GFF file contain locus-tag information for genes

This web server accepts genomes up to 8M bases for annotation
Select or drag and drop your GFF and DNA file below

DNA (.fna, .fasta or .fa) not uploaded

GFF (.gff or .gff3) not uploaded

NEW: Create a gff annotation file

FACoP sessionID:

Functional Annotation and Classification Started, please wait

May 2023. Anne de Jong [ ..]. Department of Molecular Genetics,
University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands